This is the 7th most frequent Arabic word.
لا
No.
Here, 'لا' negates the verb 'أريد' indicating a negation of the desire to do an action.
لا أريد الذهاب إلى الحفلة.
I don't want to attend the party.
Here, the first 'لا' is used as a simple negative response (no), and the second 'لا' negates the verb 'أحب' expressing a dislike.
لَا، أنا لا أحب القهوة.
No, I don't like coffee.
Here, 'لا' is part of the word 'ألا', which is used to form a negative question seeking affirmation.