This is the 6377th most frequent Chinese word.
把牢
To firmly control or guard.
In this sentence, 把牢 is used metaphorically to mean 'seize or grasp tightly' an abstract concept such as an opportunity.
你必须把牢这个机会,把它转化为成功。
You must seize this opportunity and turn it into success.
Here, 把牢 denotes the literal act of holding firmly onto something tangible, emphasizing control and possession.
在比赛中,队长把牢球权,不让对手抢走。
During the game, the captain firmly held onto the ball's possession, not letting the opponent steal it.
In this context, 把牢 refers to strictly following or adhering to processes or procedures, indicating vigilance and precision.