This is the 803rd most frequent Dutch word.
leiden
"Leiden" means "to lead" or "to guide" in English.
Here, 'leiden' is used to mean 'to guide' or 'to lead' a group or entity to a destination.
Hij wil de groep naar de top van de berg leiden.
He wants to lead the group to the top of the mountain.
In this sentence, 'leiden' is used in the context of 'to result in' or 'to cause'.
De situatie kan tot onzekerheid leiden.
The situation can result in uncertainty.
Here, 'leiden' represents 'to guide' or 'to direct' metaphorically, suggesting the river determines the path.