This is the 845th most frequent Hebrew word.
עסק
Business, deal, or occupation.
Here, 'עסק' is used to refer to a company or business entity.
העסק עלה על דרך המלך אחרי שינויים בניהול.
The business got on the right track after management changes.
In this sentence, 'עסק' is used metaphorically to mean 'concern' or 'affair' that should not involve someone.
אל תתערב, זה לא העסק שלך.
Don't interfere, this isn't your business.
Here, 'עסק' refers to an entrepreneurial venture or enterprise.