This is the 388th most frequent Italian word.
pandemia
A worldwide spread of a new disease affecting a large number of people.
The word 'pandemia' is used here as a subject referring to a specific event that caused significant changes globally, namely the pandemic.
Durante la pandemia, molte persone hanno lavorato da casa.
During the pandemic, many people worked from home.
In this case, 'pandemia' is the subject of the sentence, emphasizing its role as a significant event affecting a major aspect of society, the economy.
La pandemia ha avuto un impatto enorme sull'economia globale.
The pandemic had a huge impact on the global economy.
Here, 'pandemia' is used in the context of an ongoing situation that necessitates specific containment measures.