This is the 5585th most frequent Japanese word.
くれぐれも
"くれぐれも" means "sincerely, earnestly, or repeatedly emphasizing a request or reminder."
Here, 'くれぐれも' emphasizes the speaker's strong and sincere request or advice to the listener.
くれぐれもお身体に気をつけてください。
Please take care of your health very earnestly.
In this sentence, 'くれぐれも' conveys a pleading tone to pay thorough attention to the matter specified.
くれぐれも失礼がないようにお願いします。
Please ensure there is absolutely no unkindness.
This usage of 'くれぐれも' strongly advises caution to avoid inappropriate behavior.