This is the 1340th most frequent Japanese word.
さま
A respectful honorific suffix meaning "Mr.," "Ms.," "Mrs.," or "Lord/Lady."
In this sentence, 'さま' (sama) is used as an honorific suffix to address Mr./Ms. Kanda with utmost respect in a formal setting.
神田様、お会いできて光栄です。
Mr./Ms. Kanda, it's an honor to meet you.
Here, '様' (you) is used as a noun meaning 'appearance' or 'manner,' indicating the way something appears.
風が強い日には、波が荒れる様だ。
On windy days, it seems like the waves get rough.
In this case, 'さま' (sama) within '王様' refers to the esteemed title of 'King,' used to denote respect for the monarch.