This is the 4160th most frequent Japanese word.
ロー
"ロー" (rō) can mean "low" (e.g., low level, low gear, or low setting) depending on context.
ロー is used here to describe a setting or level as 'low', which is a phonetic borrowing from English.
この機械の操作はローです。
The operation of this machine is low.
ローソン refers to a proper noun, 'Lawson', a chain of convenience stores in Japan.
ローソンでお昼ご飯を買いました。
I bought lunch at Lawson.
ロー indicates the 'low' gear, borrowing its meaning from English for a machine-related context.