This is the 285th most frequent Portuguese word.
santa
"Santa" in Portuguese means "saint" (feminine) or "holy" (feminine).
'Santa' in this context is part of a proper noun, referring to the name of a city.
Santa Maria é uma cidade tranquila.
Santa Maria is a peaceful city.
'Santa' here is used as an adjective to describe someone's virtuous and caring character.
Ela é uma pessoa santa, sempre ajuda os necessitados.
She is a saintly person, always helping those in need.
'Santa' in this case is used in an exclamation to emphasize a quality, showing its figurative and elevated aspect.