This is the 111th most frequent Russian word.
региона
The Russian word "региона" means "region's" (possessive form) or "of the region."
The word 'региона' is used in the genitive case, defining the administration as belonging to the region.
Я работаю в администрации региона.
I work at the region's administration.
Here, 'региона' qualifies 'культура' (culture), indicating the ownership and specific geographical context.
Местная культура региона уникальна.
The local culture of the region is unique.
In this sentence, 'региона' is in the genitive case, showing the subject of the development being discussed.