This is the 468th most frequent Spanish word.
familiares
Relatives or family members.
In this sentence, 'familiares' is used as a noun to refer to family members.
Visitaré a mis familiares el fin de semana.
I will visit my relatives over the weekend.
Here, 'familiares' is used as an adjective meaning familiar.
Estos cuadros me resultan familiares.
These paintings seem familiar to me.
In this example, 'familiares' is part of the term 'médicos familiares', where it acts as an adjective describing a type of medical practice related to family.