This is the 514th most frequent Spanish word.
río
River.
Here, 'río' refers to a body of flowing water, making use of its geographical meaning.
El río serpentea a través del valle.
The river winds through the valley.
In this case, 'río' is the conjugated first person form of the verb 'reír' (to laugh), referring to an action.
Me río de tus chistes tan graciosos.
I laugh at your very funny jokes.
This usage of 'río' also pertains to the geographical meaning but in its plural form, indicating multiple entities.